Dual UTR-A novel 5′ untranslated region design for synthetic biology applications
نویسندگان
چکیده
منابع مشابه
DEFB1 gene 5′ untranslated region (UTR) polymorphisms in inflammatory bowel diseases
Valentina Zanin, Ludovica Segat, Anna Monica Bianco, Lara Padovan, Nathalia de Alencar Cunha Tavares, Sergio Crovella I University of Trieste, Institute for Maternal and Child Health – IRCCS ‘‘Burlo Garofolo’’, Trieste, Italy. II Institute for Maternal and Child Health – IRCCS ‘‘Burlo Garofolo’’Trieste, Italy. III Federal University of Pernambuco, Laboratory of Immunopathology Keizo Asami (LIKA...
متن کاملCharacterization of single nucleotide polymorphism in the 5'-untranslated region (5'-UTR) of Lactoferrin gene and its association with reproductive parameters and uterine infection in dairy cattle
Uterine infection is one of the reproductive diseases that can have disturbing postpartum uterine health in cattle. Therefore, identification of resistant genotypes to uterine infection is important. Lactoferrin (LF) is one of the major antimicrobial compounds in the normal uterine discharges of cows. We hypothesized that allelic diversity in LF gene may contribute to susceptibility or resistan...
متن کاملDevelopment of RT-PCR Using External and Internal Positive Controls Based on 5' Untranslated Region (UTR) for Molecular Detection of Avian Infectious Bronchitis Virus
Background and Aims: Infectious bronchitis virus (IBV) belongs to the group of gamma coronaviruses along with other avian coronaviruses. The disease caused by IBV can appear similar to infectious laryngotracheitis, avian influenza, and velogenic Newcastle disease, which are high priority diseases. The clinical signs can be accompanied by mortalities in broiler chickens and reduced eggshell and ...
متن کاملSynthetic Biology for Therapeutic Applications
Synthetic biology is a relatively new field with the key aim of designing and constructing biological systems with novel functionalities. Today, synthetic biology devices are making their first steps in contributing new solutions to a number of biomedical challenges, such as emerging bacterial antibiotic resistance and cancer therapy. This review discusses some synthetic biology approaches and ...
متن کاملThe ODC 3′-Untranslated Region and 5′-Untranslated Region Contain cis-Regulatory Elements: Implications for Carcinogenesis
It has been hypothesized that both the 3'-untranslated region (3'UTR) and the 5'-untranslated region (5'UTR) of the ornithine decarboxylase (ODC) mRNA influence the expression of the ODC protein. Here, we use luciferase expression constructs to examine the influence of both UTRs in keratinocyte derived cell lines. The ODC 5'UTR or 3'UTR was cloned into the pGL3 control vector upstream or downst...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Synthetic Biology
سال: 2020
ISSN: 2397-7000
DOI: 10.1093/synbio/ysaa006